impairment

Semi-spontaneous language production in Dutch speaking people with primary progressive aphasia

Primary progressive aphasia (PPA) is a neurodegenerative language disorder. Despite recent research, this disorder is studied less than vascular aphasia. There are three main accepted variants: nonfluent/agrammatic PPA (nfv-PPA), semantic PPA …

Language neuroplasticity in brain tumour patients revealed by magnetoencephalography

Language impairment in brain tumour patients may be missed since standardised tests fail to capture mild deficits. Neuroplasticity may also contribute to minimising language impairments. To address this possibility, we examined 14 patients with …

Cognitive and speech functioning in HNC: baseline prevalence and possible causes

__Background.__   The impact of treatment for head and neck cancer (HNC) on speech and cognitive functioning is well studied. Moreover, recent research has identified speech and cognitive deficits in HNC patients already prior to treatment, but …

Lexical-semantic and executive deficits revealed by computational modelling: a drift diffusion model perspective

Flexible language use requires coordinated functioning of two systems: conceptual representationsand control. The interaction between two systems can be observed when people are asked to matcha word to a picture. Participants are slower and less …

Investigating the semantic control network and its structural decline in mild cognitive impairment and mild dementia

Although the episodic and semantic memory systems have long been studied separately, recent literature revealed shared neural substrates, including the medial temporal lobe (MTL). One important aspect of semantic memory is semantic control, which …

The role of the uncinate fasciculus and inferior longitudinal fasciculus in healthy and disordered language production

White-matter bottleneck in small vessel disease: A lesion-symptom mapping study of executive-language functions

Cerebral small vessel disease (CSVD), characterized by the presence of white matter lesions (WML), is among the main causes of vascular cognitive impairment. The most well-studied cognitive domains showing impairment in CSVD are executive functioning …

Cognitive and speech functioning in head and neck cancer

Project

Assessment of Neurocognitive Impairment and Speech Functioning Before Head and Neck Cancer Treatment

We documented cognitive and speech functioning before treatment in individuals with head and neck cancer in a prospective cohort study. Results indicated a high prevalence of speech and cognitive impairment. Patient-reported speech and cognitive function were associated with each other, whereas objective cognitive measures were not associated with patient-reported measures.

Lexical selection with competing distractors: Evidence from left temporal lobe lesions

According to the competition account of lexical selection in word production, conceptually driven word retrieval involves the activation of a set of candidate words in left temporal cortex and competitive selection of the intended word from this set, …