white matter

The functional neuroanatomy of the left temporal lobe white matter – an interdisciplinary approach based on intraoperative and comparative studies.

The left temporal lobe is claimed to be involved in language comprehension in both the classical (Wernicke, 1874) and contemporary dual-pathway models for language processing (Hickok & Poeppel, 2007, Roelofs, 2014), but the role of neuroanatomical …

Investigating the semantic control network and its structural decline in mild cognitive impairment and mild dementia

Although the episodic and semantic memory systems have long been studied separately, recent literature revealed shared neural substrates, including the medial temporal lobe (MTL). One important aspect of semantic memory is semantic control, which …

The frontal aslant white matter tract (FAT) and semantic selection in word production

The frontal aslant tract (FAT) is a white matter structure joining the anterior supplementary and pre-supplementary motor area (SMA and pre-SMA) to the inferior and middle frontal gyri. FAT shows leftward asymmetry (Catani et al., 2012), which …

The role of the uncinate fasciculus and inferior longitudinal fasciculus in healthy and disordered language production

The role of ventral fiber pathways in healthy and disordered language production

While neuroimaging research on language production has traditionally focused primarily on grey matter, several recent studies highlight the involvement of ventral and dorsal white matter pathways. A debated issue concerns the exact functional role of …

White-matter bottleneck in small vessel disease: A lesion-symptom mapping study of executive-language functions

Cerebral small vessel disease (CSVD), characterized by the presence of white matter lesions (WML), is among the main causes of vascular cognitive impairment. The most well-studied cognitive domains showing impairment in CSVD are executive functioning …

Roles of ventral versus dorsal pathways in language production: An awake language mapping study

Human language is organized along two main processing streams connecting posterior temporal cortex and inferior frontal cortex in the left hemisphere, travelling dorsal and ventral to the Sylvian fissure. Some views propose a dorsal motor versus …

Neuroplasticity of language in left-hemisphere stroke: evidence linking subsecond electrophysiology and structural connections

Our understanding of neuroplasticity following stroke is predominantly based on neuroimaging measures that cannot address the subsecond neurodynamics of impaired language processing. We combined behavioral and electrophysiological measures and …