Language neuroplasticity in brain tumour patients revealed by magnetoencephalography

Language impairment in brain tumour patients may be missed since standardised tests fail tocapture mild deficits. Neuroplasticity may also contribute to minimising languageimpairments. To address this possibility, we examined 14 patients with …

Investigating the semantic control network and its structural decline in mild cognitive impairment and mild dementia

Although the episodic and semantic memory systems have long been studied separately, recent literature revealed shared neural substrates, including the medial temporal lobe (MTL). One important aspect of semantic memory is semantic control, which …

The role of the uncinate fasciculus and inferior longitudinal fasciculus in healthy and disordered language production

The role of ventral fiber pathways in healthy and disordered language production

While neuroimaging research on language production has traditionally focused primarily on grey matter, several recent studies highlight the involvement of ventral and dorsal white matter pathways. A debated issue concerns the exact functional role of …

White-matter bottleneck in small vessel disease: A lesion-symptom mapping study of executive-language functions

Cerebral small vessel disease (CSVD), characterized by the presence of white matter lesions (WML), is among the main causes of vascular cognitive impairment. The most well-studied cognitive domains showing impairment in CSVD are executive functioning …

Cognitive and speech functioning in head and neck cancer


Assessment of Neurocognitive Impairment and Speech Functioning Before Head and Neck Cancer Treatment

We documented cognitive and speech functioning before treatment in individuals with head and neck cancer in a prospective cohort study. Results indicated a high prevalence of speech and cognitive impairment. Patient-reported speech and cognitive function were associated with each other, whereas objective cognitive measures were not associated with patient-reported measures.

Lexical selection with competing distractors: Evidence from left temporal lobe lesions

According to the competition account of lexical selection in word production, conceptually driven word retrieval involves the activation of a set of candidate words in left temporal cortex and competitive selection of the intended word from this set, …

A valid alternative for in-person language assessments in brain tumor patients: feasibility and validity measures of the new TeleLanguage test

Background: Although language deficits after awake brain surgery are usually milder than post stroke, postoperative language assessments are needed to identify these. Follow-up of brain tumor patients in certain geographical regions can be difficult …

Lesion evidence for a critical role of left posterior but not frontal areas in alpha-beta power decreases during context-driven word production

Studies suggest that alpha–beta power decreases index word retrieval in context-driven word production. We recorded the electroencephalogram from patients with stroke lesions encompassing the left lateral-temporal and inferior-parietal regions or left lateral-frontal lobe. Results indicate a critical role for the left posterior, but not frontal cortex, in generating the alpha–beta power decreases underlying context‐driven word production.